Nitroxoline Tablets 50 mg, 50 pcs.

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По рецепту врача
50 pcs.
Pharmaceutical form
Active substances

Pharmachologic effect

Nitroxoline - an antimicrobial and antiprotozoal broad spectrum for the treatment of urinary tract infections. Nitroxoline selectively inhibits the synthesis of bacterial DNA, complexed with metal-containing enzymes, microbial cells and acts both on Gram-positive bacteria: Staphylococcus spp. (Including S.aureus), Streptococcus spp. (Including beta-haemolytic streptococci, Streptococcus pneumoniae, Enterococcus faecalis), Corynebacterium spp, Bacillus subtilis.; and gram-negative microorganisms: N.gonorrhoeae, E.coli, Proteus spp, Klebsiella spp, Salmonella spp, Shigella spp, Enterobacter spp.

Nitroxoline also active against Mycobacterium tuberculosis, Trichomonas vaginalis, some species of fungi (Candida spp., Dermatophytes, molds, some pathogens of deep mycoses).


Once inside Nitroxoline well absorbed from the digestive tract. Provided mainly kidneys unchanged. In a single dose of 100 mg minimal bacteriostatic concentration in urine persists until 3 hours. After administration of 400 mg - 7 hours.

Therapeutic Indications

 Infectious and inflammatory diseases of the urinary tract caused by susceptible microorganisms (including pyelonephritis, cystitis, urethritis), epididymitis;
- Infected adenoma or carcinoma, prostate and others).
- Prevention of infectious complications during diagnostic and therapeutic interventions (catheterization, cystoscopy, after operations on the kidneys and urinary tract).


Renal function, accompanied by oligo-or anuria, severe liver disease, deficiency of glucose-6-phosphate dehydrogenase, cataracts, optic neuritis, pregnancy, lactation, hypersensitivity to drugs quinoline series.

Nitroxoline  contraindicated during pregnancy and lactation (breastfeeding).

Special instructions

Due to Nitroxoline usage urine is painted in a saffron-yellow color.


Active ingredient:  Nitroxoline - 50 mg.

Posology and Administration

Adult dose Nitroxoline is 600-800 mg / day. Multiplicity of reception - 3-4 times / day. with an interval of 6-8 hours The course of treatment -. 10-14 days.

Maximum dose: 1-1.2 g

For children the dose is 10-30 nitroksolin mg / kg / day. in 3-4 hours.

Side effects

From the digestive system: nausea, vomiting, loss of appetite; in rare cases - impaired liver function.

Allergic reactions: skin rash, pruritus.

From the central and peripheral nervous system: in rare cases - ataxia, headache, paresthesia, polyneuropathy; long-term use, a case of neuritis of the optic nerve.

Cardio-vascular system: in rare cases - tachycardia.

Medicament interactions

In a joint application with drugs tetracycline nitroxoline group observed summation of the effects of each drug nystatin and Levorinum - potentiation of action. To avoid summation of negative neurotropic effect, can not be combined with Nitroxoline nitrofurans.


Overdose nitroxoline possible and shows the development of the following symptoms - tachycardia, nausea, vomiting, allergic rashes, headache and disturbance sensitivity. Overdose Treatment is a temporary cancellation of the preparation and use of symptomatic drugs.

Storage conditions

In the dark place at a temperature no higher than 20 ° C.